Website of D lab in Nagoya University

Welcome to the D lab's website!

Priciple of AFMDynamic actions of proteins, such as the conformational change and protein-protein interactions, are crucial to their biological functions. Usually, protein motions are unsynchronized and, therefore, difficult to monitor with ensemble-averaged experiments. In order to reveal the dynamic behavior of proteins, single-molecule approaches are indispensable. We are developing and implementing novel single-molecule techniques based on high-speed atomic force microscopy (HS-AFM). These techniques enable real-time visualization of molecules in action and allow to elucidate the function mechanisms of biological molecules with dynamic actions relevant to their unique tasks.

News

October 31, 2017 Our collaborative paper with Prof. Kato (IMS, OIB, NAgoya Chity Univ.), Prof. Sato and Prof. Yagi (Nagoya City Univ.) has been accepted by Scientific Reports.

October 27, 2017 Our collaborative paper with Prof. Iino, Dr. Nakamura (IMS), Prof. Watanabe, Prof. Suzuki, Prof. Sugimoto (Niigata Univ.) and Prof. Murata (NIPS) has been accepted by PCCP.

October 7, 2017 Our collaborative paper with Prof. Minamino, Dr. Terahara, Prof. Namba (Osaka Univ.) and Prof. Kodera, Prof. Ando (Kanazawa Univ.) has been accepted by Science Advances.

September 20, 2017 Toshiya Kozai, graduate student, was awarded the Student Presentation Award at the 55th Annual Meeting of the Biophysical Society Japan (photo). Congratulations!

   

September 20, 2017 Our collaborative paper with Prof. Shibata, Prof. Kodera, Prof. Ando (Kanazawa Univ.) and Prof. Nishimasu, Prof. Nureki (Univ. of Tokyo) has been accepted by Nature Communications.

   

September 9, 2017 Our collaborative paper with Prof. Sato, Prof. Kato (Nagoya City Univ.), Prof. Kamikubo (Nara Institute of Science and Technology) and Prof. Murata (National Institute for Physiological Sciences) has been accepted by Scientific Reports.

    

July 15, 2017 Our collaborative paper with Prof. Onoda, Prof. Hayahi (Osaka Univ.) and Prof. Igarashi (Univ. of Tokyo) has been accepted by Chemical Science.

July 14, 2017  Our review paper has been accepted by BBA General Subjects (a special issue on"Biophysical Exploration of Dynamical Ordering of Biomolecular Systems"). The co-author is Prof. Simon Scheuring in Cornell University.

July 13, 2017  Our collaborative paper with Prof. Suzuki and Mr. Matsui (Shinshu Univ.) has been accepted by Angewandte Chemie International Edition.

April 1, 2017  The D lab has been launched at the Department of Physics.

Events

November 7-8, 2017   2nd Japan-Korea Single-Molecule Biophysics Workshop@Seoul, Korea

December 3-9, 2017   MHS 2017: 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science@Nagoya

December 6-9, 2017   ConBio2017: Consortium of Biological Sciences 2017@Kobe

December 12-14   JSPS Grant‐in‐Aid for Scientific Research on Innovative Areas"Studying the Function of Soft Moleculear Systems by the Concerted Use of Theory and Experiment" Area Meeting@Okinawa

January 20, 21   The 6th International Symposium on Dynamic Ordering of Biomolecular Systems for Creation of Integrated Functions@Hamamatsu