Website of D lab in Nagoya University

Welcome to the D lab's website!

Priciple of AFMDynamic actions of proteins, such as the conformational change and protein-protein interactions, are crucial to their biological functions. Usually, protein motions are unsynchronized and, therefore, difficult to monitor with ensemble-averaged experiments. In order to reveal the dynamic behavior of proteins, single-molecule approaches are indispensable. We are developing and implementing novel single-molecule techniques based on high-speed atomic force microscopy (HS-AFM). These techniques enable real-time visualization of molecules in action and allow to elucidate the function mechanisms of biological molecules with dynamic actions relevant to their unique tasks.

The D lab was established from the former J lab after Prof. Kouyama's retirement by Takayuki Uchihashi, who moved here from Kanazawa University on April 1st 2017. In April 2018 two fourth year students joined the other members (one PhD student from Kanazawa University, two researchers). Let's all work together to create a new and interesting lab!

By the way, it is often asked what the "D" of the "D lab" means: It is the first letter of "dynamics".

News

October 1, 2019  Feng-Yueh Chan joined our gropu as a PhD student (G30 program).

September 24, 2019  Our collaborative paper with Dr. Shihoya, Prof. Nureki (Univ. Tokyo), Prof. Kandori, Prof. Furutani (Nagoya Int. Tech.) and Prof. Inoue (Univ. Tokyo, ISSP) has been published in Nature.

August 7, 2019  T. U. won the "Best Conference Paper Award" at IEEE 3M-Nano 2019.

August 7, 2019  H. W. was selected as a filasist for the "Best Conference Application Award" at IEEE 3M-Nano 2019.

August 2, 2019  Our collaborative paper with Prof. Kato (ExCELLS) and Prof.Uchiyama (Osaka Univ.) has been accepted by Scientific Reports.

July 16, 2019  Our collaborative paper with Prof. Suzuki (Shinshu Univ.) has been accepted by Chemical Communications.

May 7, 2019  Our collaborative paper with Prof. Kato (ExCELLS), Prof.Uchiyama (Osaka Univ.) and Prof. Murata (NIPS) has been accepted by International Journal of Molecular Sciences.

April 29, 2019  Our collaborative paper with Prof. Michael Higgins and Dr. Feng (Wollongong Univ., Australia) has been accepted by Journal of Molecular Biology.

April 25, 2019  Our collaborative paper with Prof. Suzuki, Mr. Nisizawa (Shinshu Univ.), Prof. Urayama (Kyoti Institute of Technology) and Prof. Shibayama, Dr. Kurha (Univ. Tokyo) has been accepted by Angewandte Chemie International Edition.

April 16, 2019  Our collaborative paper with Dr. Sumino, Dr. Sumikama (Kanazawa Univ.) and Prof. Oiki (Fukui Univ.) has been accepted by Science Advances.

April 10, 2019  Our collaborative paper with Prof. Hirota, Prof. Kamikubo (NAIST) and Prof. Shimizu (KEK) has been accepted by ACS Synthetic Biology.

April 8, 2019  Our collaborative paper with Prof. Suzuki (Shinshu Univ.) has been accepted by Angewandte Chemie International Edition.

Past News

Events